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However, the exact cause of osteochondroma is unknown. Osteochondrosis is a term used to describe a group of disorders that affect the growing skeleton. Osteochondrosis [ os″ te- o- kon- dro´ sis] a disease of the growth ossification centers in children, beginning as a degeneration or necrosis followed by regeneration or recalcification; known by various names, depending on the bone involved. An osteochondroma is a benign ( noncancerous) tumor that develops during childhood or adolescence. Histologically, osteochondrosis is characterized by persistence of chondrocytes in the mid to late hypertrophic zone with failure of vascular invasion and subsequent osteogenesis. In about 10– 15% of all cases no genomic alterations are detected. The mechanism behind the formation of multiple osteochondroma is large genomic deletions of EXT1 and EXT2 genes. It is an abnormal growth that forms on the surface of a bone near the growth plate. An osteochondroma is made up of both bone and cartilage. Most often, it affects the long bones in the leg, the pelvis, or the shoulder blade. Osteochondrosis defor´ mans ti´ biae tibia vara. Os· te· o· chon· dro· sis ( os' tē- ō- kon- drō' sis), Any of a group. Osteochondroses can also occur as a result of athletic activity and sports injuries. These disorders result from abnormal growth, injury, or overuse of the developing growth plate and. Osteochondroma is an overgrowth of cartilage and bone that happens at the end of the bone near the growth plate. Dec 12, · Osteochondrosis is a self- limiting developmental derangement of normal bone growth, primarily involving the centers of ossification in the epiphysis. Osteochondrosis is a failure of normal endochondral ossification, resulting in thickening and retention of the hypertrophic zone of the growth cartilage. Osteocondroză postmenopauză.
Osteochondrosis is a family of orthopedic diseases of the joint that occur in children, adolescents and other rapidly growing animals, particularly pigs, horses, dogs, and broiler chickens. The identified mechanism behind solitary osteochondromas is the homozygous deletions of the EXT1 gene. It usually begins in childhood as a degenerative or necrotic condition. These lesions may be precipitated by abnormal chondrocyte. Osteochondroma is the most common noncancerous bone growth. Osteochondrosis is almost exclusively found in children and teenagers up to around age 20.